Abstract: A new structure road detection algorithm based on open uniform B-spline curve model is proposed. The algorithm is composed of the following steps: First, Canny edge detection is used to extract road edges, then road marking lines are detected from the edge map by the least squares method, finally, the road model is fitted after the central points of the road are gotten from the lane markings. In order to accurately locate the position of road bend, the algorithm introduces the maximum deviation of position shift (MDPS) method to search control points. A large number of experiments show that the algorithm is fast, stable, flexible, and could meet the requirements of intelligent navigation.